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Beaucage reagent

Beaucage reagent

100 INR/Kilograms
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Product Details:

  • CAS No 66304-01-6
  • Product Type Chemical Reagent
  • Properties Stable in dry conditions, sensitive to moisture
  • HS Code 29309099
  • Poisonous YES
  • Structural Formula As per image (benzoyl group with a thiol and sulfonyl moiety)
  • Shelf Life 12-24 months under recommended storage conditions
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Beaucage reagent Price And Quantity

  • 100 INR/Kilograms
  • 10 Kilograms

Beaucage reagent Product Specifications

  • 29309099
  • Soluble in acetonitrile, dichloromethane; slightly soluble in water
  • Stable in dry conditions, sensitive to moisture
  • Chemical Reagent
  • Not Applicable (neutral solid)
  • 66304-01-6
  • Not determined
  • C7H5NO2S2
  • 245-986-2
  • White to off-white crystalline solid
  • >=98%
  • 12-24 months under recommended storage conditions
  • As per image (benzoyl group with a thiol and sulfonyl moiety)
  • YES
  • Analytical, Molecular Biology Grade
  • 199.25 g/mol
  • Used in oligonucleotide synthesis for the sulfurization of phosphate triesters
  • Solid (Powder or Crystalline)
  • Benzoylthiotetrazole, organic solvents
  • Odorless
  • Store at 2-8C in a tightly closed container, protect from moisture and air
  • 1.458 Gram per cubic centimeter(g/cm3)
  • Crystalline/Powder
  • 103-106 C
  • Sulfurization reagent in automated oligonucleotide synthesis
  • Acetonitrile, dichloromethane, toluene
  • Dispose of as hazardous organic laboratory waste
  • >110C
  • Use with adequate ventilation, avoid moisture exposure
  • 1,2-Benzoxathiin-3-one, 1,1-dioxide
  • Irritant
  • NMR, MS available upon request
  • 3H-1,2-Benzodithiol-3-one 1,1-dioxide
  • 1g, 5g, 10g, 25g

Beaucage reagent Trade Information

  • mumbai
  • Cash Advance (CA), Cash in Advance (CID), Telegraphic Transfer (T/T)
  • Yes
  • Contact us for information regarding our sample policy
  • Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa
  • All India

Product Description

Chemical name: Beaucage reagent

Synonyms: 3H-1,2-Benzodithiol-3-one1,1-dioxide

Cas no: 66304-01-6

Purity: 98%

Molecular formula: C7H4O3S2

Molecular Weight:200.2

Appearance:solid

Efficient Sulfurization Agent for Oligonucleotide Synthesis

Beaucage reagent is a highly effective sulfurization compound crucial for incorporating sulfur into phosphate backbones during the automated synthesis of oligonucleotides. Its robust performance ensures precise modification, which is essential for developing reliable therapeutic and diagnostic oligonucleotides. The reagent is stable under dry conditions, allowing scientists to synthesize high-quality oligonucleotide analogs with enhanced biological stability.


Strict Quality and Packaging Standards

Offered as a solid-either crystalline or powder form-in sizes ranging from 1g to 25g, Beaucage reagent is manufactured to analytical and molecular biology grade specifications. Each batch meets a purity of at least 98%, ensuring consistent results. The product is packaged to protect it from moisture and air, supporting a shelf life of 12-24 months when stored between 2-8C in tightly closed containers.

FAQ's of Beaucage reagent:


Q: How is Beaucage reagent used in oligonucleotide synthesis?

A: Beaucage reagent serves as a sulfurization agent in automated oligonucleotide synthesis, converting phosphate triesters into phosphorothioate linkages to enhance the stability and activity of synthesized oligonucleotides.

Q: What solvents are compatible with Beaucage reagent during synthesis processes?

A: The reagent is compatible with acetonitrile, dichloromethane, and toluene. It dissolves readily in these solvents, supporting efficient sulfurization reactions during DNA or RNA synthesis.

Q: When should Beaucage reagent be handled with special precautions?

A: Special precautions are necessary at all times; it is classified as an irritant and is poisonous. Use with adequate ventilation, avoid direct skin contact, and prevent exposure to moisture to maintain reagent integrity and ensure safety.

Q: Where should Beaucage reagent be stored to maximize shelf life?

A: Store the reagent at 2-8C in a tightly closed container, away from air and moisture. Proper storage conditions help ensure product stability for 12-24 months.

Q: What is the procedure for disposing of unused Beaucage reagent?

A: Dispose of Beaucage reagent as hazardous organic laboratory waste in accordance with institutional and environmental safety protocols, due to its toxic and irritant properties.

Q: What are the main benefits of using Beaucage reagent in molecular biology applications?

A: The reagent provides rapid and efficient sulfurization, yielding oligonucleotides with modified backbones that offer increased resistance to nuclease degradation, which is beneficial for research and therapeutic applications.

Q: Can I obtain analytical data such as NMR or MS for Beaucage reagent?

A: Yes, NMR and mass spectral data are available upon request to verify the reagent's identity and purity before use in critical synthesis steps.

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    NATIONAL ANALYTICAL CORPORATION - CHEMICAL DIVISION
    GST : 27AWSPS9814L1ZF
  • Kesarkunj, Rm No. 9, Vasanji Lalji Road, Kandivali (W), Mumbai - 400067, Maharashtra, India
  • Phone : 07971189995
  • Mr Nilesh Shah (Director)
  • Mobile : 07971189995
  • Mr Dharmik Shah
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