Product Description
Chemical Name: (3As,4r,6ar)-6-((benzyloxy)methyl)-5-fluoro-2,2-dimethyl-4,6a-dihydro-3ah-cyclopenta[d1,3]dioxol-4-ol
Synonyms : (3aS,4R,6aR)-6-((Benzyloxy)methyl)-5-fluoro-2,2-dimethyl-4,6a-dihydro-3aH-cyclopenta[d1,3]dioxol-4-ol|
(3aR,6R,6aS)-5-fluoro-2,2-dimethyl-4-(phenylmethoxymethyl)-6,6a-dihydro-3aH-cyclopenta[d1,3]dioxol-6-ol
CAS No : 491578-02-0
Purity : 95%
MolecularFormula : C16H19FO4
Molecular Weight: 294.3
Specialized Chiral IntermediateThis compound features specific (3As,4r,6ar) stereochemistry and is highly valued for its chiral properties in advanced synthesis. Frequently used in the pharmaceutical sector, the presence of benzyloxy, dioxolane, and fluorine functionalities lend versatility for constructing more complex molecules.
Physical and Chemical AttributesWith a melting point between 122126C, a density of 1.23 g/cm, and purity greater than 98%, this solid is characterized by its crystalline appearance and faint odor. It demonstrates strong solubility in organic solvents like dichloromethane (DCM) and methanol, but limited water solubility.
Proper Storage and HandlingTo ensure a two-year shelf life, store this compound in a sealed amber glass vial at 28C, protected from light and moisture. It remains stable under normal conditions and has not been classified as hazardous by GHS standards, making it suitable for laboratory use with standard precautions.
FAQs of (3As,4r,6ar) -6-((benzyloxy)methyl)-5-fluoro-2,2-dimethyl-4,6a-dihydro-3ah-cyclopenta[d][1,3]dioxol-4-ol:
Q: How should (3As,4r,6ar)-6-((benzyloxy)methyl)-5-fluoro-2,2-dimethyl-4,6a-dihydro-3ah-cyclopenta[d][1,3]dioxol-4-ol be stored for maximum stability?
A: Store the compound at 28C in a dry, cool environment, away from direct sunlight and moisture. Use a sealed amber glass vial or container, as recommended by the supplier, to optimize its stability and extend its shelf life.
Q: What are the main uses of this compound in the laboratory?
A: This compound serves as a key intermediate in synthetic pathways, especially for constructing fluorinated and chiral frameworks used in pharmaceutical research and development. It is intended strictly for research and analytical applications, not for food, drug, or household use.
Q: When does the compound decompose, and what precautions should be taken?
A: The compound decomposes prior to boiling; it should not be heated excessively. Always handle it within recommended temperature ranges and under standard laboratory conditions to avoid decomposition and ensure consistent results.
Q: Where can I find details about the compounds optical activity?
A: Information regarding optical activity, including specific rotation values, can be found in the Certificate of Analysis (COA) provided by the supplier. This data verifies the chiral nature and purity of the product.
Q: What benefits does the fluorinated and chiral structure offer in synthesis?
A: The presence of a chiral center and a fluorinated scaffold enhances the compounds utility in building blocks for pharmaceuticals, enabling researchers to synthesize molecules with more desirable biological properties and improved selectivity.
Q: How is the compound typically handled and dissolved in laboratory settings?
A: It is usually dissolved in organic solvents such as dichloromethane (DCM) or methanol due to its low water solubility. Standard laboratory handling procedures apply, since it is not classified as hazardous.
Q: Is this compound classified as hazardous or poisonous, and what safety measures are recommended?
A: This compound is not classified as hazardous under GHS and is not considered poisonous. Nevertheless, its essential to use appropriate laboratory safety standards, such as gloves and eye protection, to handle the solid and solutions safely.