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3,4-Difluorobenzenesulfonyl chloride

3,4-Difluorobenzenesulfonyl chloride

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Product Details:

  • Solubility Insoluble in water; soluble in organic solvents such as dichloromethane and chloroform
  • CAS No 145758-05-0
  • Appearance White to off-white solid
  • HS Code 29041090
  • Smell Pungent, irritating odor
  • Application Pharmaceutical intermediate, agrochemical synthesis, organic synthesis
  • Physical Form Powder or crystalline solid
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3,4-Difluorobenzenesulfonyl chloride Price And Quantity

  • 1 Number
  • Strong bases, strong oxidizers, water
  • HDPE lined drums or bottles
  • Use personal protective equipment, avoid exposure, work in well-ventilated area
  • Handle as a hazardous chemical; follow local regulatory requirements
  • 2927
  • 6.1 (Toxic substances)
  • Stable under recommended storage conditions; sensitive to moisture
  • Releases toxic gases including HCl, SOx, and HF under fire conditions
  • >110 C
  • 251 C (decomposes)

3,4-Difluorobenzenesulfonyl chloride Product Specifications

  • Powder or crystalline solid
  • Pharmaceutical intermediate, agrochemical synthesis, organic synthesis
  • Pungent, irritating odor
  • 29041090
  • 145758-05-0
  • White to off-white solid
  • Insoluble in water; soluble in organic solvents such as dichloromethane and chloroform
  • 212.60 g/mol
  • >=98%
  • See image or C6H3ClF2O2S structural representation
  • 1.48 Gram per cubic centimeter(g/cm3)
  • 3,4-Difluorobenzenesulfonyl chloride, no additives
  • 401-430-3
  • Organic intermediate, chemical reagent
  • 47-50 C
  • Store in cool, dry, and well-ventilated area, tightly sealed container, protect from moisture
  • Crystalline powder
  • 2 years if stored properly
  • Not determined
  • C6H3ClF2O2S
  • Yes, toxic if ingested or inhaled
  • Analytical/Industrial grade
  • Used as a sulfonylating agent in synthesis of active compounds
  • High chemical reactivity, electrophilic sulfonyl chloride group, stable under recommended conditions
  • Strong bases, strong oxidizers, water
  • HDPE lined drums or bottles
  • Use personal protective equipment, avoid exposure, work in well-ventilated area
  • Handle as a hazardous chemical; follow local regulatory requirements
  • 2927
  • 6.1 (Toxic substances)
  • Stable under recommended storage conditions; sensitive to moisture
  • Releases toxic gases including HCl, SOx, and HF under fire conditions
  • >110 C
  • 251 C (decomposes)

3,4-Difluorobenzenesulfonyl chloride Trade Information

  • mumbai
  • Cash Advance (CA), Cash in Advance (CID), Telegraphic Transfer (T/T)
  • 1000 Number Per Month
  • 7 Days
  • Yes
  • Contact us for information regarding our sample policy
  • Central America, Australia, South America, Western Europe, Middle East, North America, Asia, Eastern Europe, Africa
  • All India

Product Description

Chemical Name: 3,4-Difluorobenzenesulfonyl chloride

Synonyms :3,4-Difluorobenzene-1-Sulfonyl Chloride

CAS No : 145758-05-0

Purity : 97%

MolecularFormula :C6H3ClF2O2S

Molecular Weight:212.6

Appearance : Liquid

Key Properties and Hazard Information

This compound features a reactive sulfonyl chloride group and exhibits high chemical reactivity, making it invaluable in synthesis. It is toxic (Hazard Class 6.1) and sensitive to moisture, with a pungent odor and crystalline form. Its stability is maintained when stored in cool, dry, and ventilated environments, away from incompatible substances like strong bases and oxidizers.


Safe Handling and Storage Recommendations

Proper handling includes use of personal protective equipment and working in well-ventilated areas. The product should be stored in tightly sealed, HDPE-lined containers to prevent moisture ingress. Always follow local transport regulations due to its toxic nature, and avoid conditions that cause decomposition, which may release hazardous gases.


Applications in Synthesis and Industry

3,4-Difluorobenzenesulfonyl chloride is essential for synthesizing pharmaceutical intermediates, agrochemicals, and various organic compounds. Its reactivity allows chemists to introduce sulfonyl groups efficiently, facilitating the development of novel active molecules for commercial and research uses.

FAQ's of 3,4-Difluorobenzenesulfonyl chloride:


Q: How should 3,4-Difluorobenzenesulfonyl chloride be safely handled and stored?

A: Always use personal protective equipment, work in a well-ventilated area, and avoid skin or respiratory exposure. Store in a tightly sealed HDPE-lined container, out of direct contact with moisture, in a cool, dry, and well-ventilated space.

Q: What are the main applications and benefits of using 3,4-Difluorobenzenesulfonyl chloride?

A: It serves as a potent sulfonylating agent in the synthesis of pharmaceutical intermediates, agrochemicals, and specialty organic compounds, enabling efficient introduction of sulfonyl groups for advanced compound creation.

Q: When does decomposition occur, and what hazardous materials can be released?

A: Decomposition takes place at its boiling point (251C) or under fire conditions, releasing toxic gases such as hydrogen chloride, sulfur oxides, and hydrogen fluoride, which require appropriate emergency measures.

Q: Where should this compound be transported and stored to maximize shelf life?

A: Transport and storage should occur in HDPE-lined drums or bottles, in compliance with local hazard regulations. Keep the product in a cool, dry, and ventilated area, away from strong bases, oxidizers, and water to preserve stability and a shelf life of up to 2 years.

Q: What personal precautions are needed to work safely with this material?

A: Wear chemical-resistant gloves, safety goggles, and protective clothing. Operate in a well-ventilated environment or use appropriate fume extraction to minimize exposure to toxic vapors or dust.

Q: How insoluble is 3,4-Difluorobenzenesulfonyl chloride in water, and which solvents can dissolve it?

A: This compound is insoluble in water but dissolves readily in organic solvents such as dichloromethane and chloroform, making it suitable for diverse organic synthesis processes.

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    NATIONAL ANALYTICAL CORPORATION - CHEMICAL DIVISION
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  • Kesarkunj, Rm No. 9, Vasanji Lalji Road, Kandivali (W), Mumbai - 400067, Maharashtra, India
  • Phone : 08071630254
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