Product Description
Chemical Name: 2-Acetamido-5-fluorophenylboronicacid, pinacol ester
Synonyms : 2-Acetamido-5-fluorophenylboronicacid, pinacol ester |
N-[4-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide|
2-Acetamido-5-fluorophenylboronicacid pinacol ester
Cas No : 1150271-55-8
Purity : 98%
MolecularFormula : C14H19BFNO3
Molecular Weight: 279.1
Appearance: Solid
Key Features and BenefitsWith a molecular weight of 279.12 g/mol and a melting point of 123-125C, this boronic ester offers reliable performance in chemical synthesis. Its stability under recommended storage conditions ensures consistent results, particularly in pharmaceutical research and organic synthesis applications.
Recommended Storage and HandlingTo preserve its purity and efficacy, store 2-Acetamido-5-fluorophenylboronic acid, pinacol ester at temperatures between 2-8C, away from moisture and light. Its hygroscopic nature means it should be handled rapidly and sealed tightly when not in use to prevent degradation.
Applications in Organic SynthesisThis compound is ideal for Suzuki-Miyaura coupling reactions, facilitating the formation of biaryl and related structures pivotal in drug development and advanced materials research. Its high reactivity and purity make it a preferred choice for demanding synthesis protocols.
FAQ's of 2-Acetamido-5-fluorophenylboronic acid, pinacol ester:
Q: How should 2-Acetamido-5-fluorophenylboronic acid, pinacol ester be properly stored to maintain its stability?
A: Store the compound at 2-8C in tightly sealed containers, protected from moisture and light, to ensure it remains stable for up to 24 months.
Q: What is the primary application of this boronic ester in laboratory settings?
A: It is primarily utilized in Suzuki-Miyaura coupling and other cross-coupling reactions, which are essential in organic synthesis and pharmaceutical research for constructing complex biaryl compounds.
Q: When is it recommended to open the container for use?
A: Open the container only when you are ready to use the material to minimize air and moisture exposure, as the compound is hygroscopic and sensitive to environmental conditions.
Q: Where can this product be sourced, and what packaging is provided?
A: 2-Acetamido-5-fluorophenylboronic acid, pinacol ester is supplied by traders and suppliers in India and comes in tightly sealed containers to maintain product integrity during transport and storage.
Q: What processes benefit most from using this compound?
A: Chemical synthesis processes-especially Suzuki-Miyaura cross-coupling reactions-benefit from its high reactivity and purity, making it valuable in pharmaceutical R&D and organic synthesis.
Q: Is there any special hazard or safety information to consider during handling?
A: No specific hazard statements are provided, but standard laboratory precautions should be observed due to the lack of comprehensive safety data.
Q: What is the observed physical appearance and solubility of this compound?
A: It appears as a white to off-white crystalline powder, is odorless or has a faint characteristic smell, and is soluble in common organic solvents such as DMSO, DMF, and methanol.