Product Description
Chemical Name: 2,3-Dihydro-1-benzofuran-5-sulfonyl chloride
Synonyms :dihydrobenzofuran-5-sulfonyl chloride
CAS No : 115010-11-2
Purity : 97%
MolecularFormula :C8H7ClO3S
Molecular Weight:218.7
Appearance : SolidKey Features and Uses2,3-Dihydro-1-benzofuran-5-sulfonyl chloride is prized in laboratory settings for its efficiency as a sulfonylating agent. Its sulfonyl chloride group enables the synthesis of sulfonamide derivatives, which are critical intermediates in pharmaceuticals and agrochemicals. Due to its sensitivity to moisture and high purity (>98%), it is ideal for research and advanced organic reactions.
Safe Handling and StorageProper handling and storage of this compound are essential to maintain safety and product integrity. The substance is corrosive and irritant; thus, always use protective equipment, including gloves, goggles, and lab coats. Store in a cool, dry place, protected from moisture, ideally under an inert atmosphere to ensure stability and preserve shelf life.
Transport and Regulatory InformationClassified as corrosive and assigned UN Number 3261 for transport (where applicable), this compound must be shipped following stringent chemical transportation regulations. The HS Code 29349900 applies for customs purposes, and both traders and end-users in India must comply with local and international safety guidelines.
FAQ's of 2,3-Dihydro-1-benzofuran-5-sulfonyl chloride:
Q: How should 2,3-Dihydro-1-benzofuran-5-sulfonyl chloride be safely stored?
A: It should be kept tightly sealed in a dry, cool, and well-ventilated area, away from moisture. If possible, store under an inert atmosphere such as nitrogen or argon to enhance stability and extend its shelf life.
Q: What are the main applications of this compound in research or industry?
A: This compound is primarily used as a sulfonylating agent in organic synthesis, facilitating the creation of sulfonamide derivatives for pharmaceutical and agrochemical research.
Q: When is it necessary to handle this substance with extra precautions?
A: Extra precautions must be taken during transfer, weighing, or reactions, since the compound is moisture-sensitive, corrosive, and can cause harm if inhaled or ingested. Appropriate PPE must be worn at all times during handling.
Q: Where does this compound show solubility, and why is it important for synthesis?
A: 2,3-Dihydro-1-benzofuran-5-sulfonyl chloride is soluble in organic solvents such as dichloromethane and chloroform. This property is crucial for use in organic reactions where water must be excluded to prevent hydrolysis.
Q: What is the benefit of using this reagent in organic synthesis?
A: Its high reactivity and purity make it valuable for constructing sulfonamide bonds. This expedites the synthesis of complex molecules in medicinal chemistry and agrochemical development.
Q: How should this compound be transported according to regulations?
A: It must be handled as a corrosive substance under UN Number 3261 and compliant with chemical shipment guidelines, using appropriate packaging and labeling to ensure safe transport.