Product Description
Chemical Name: 3-Amino-5-trifluoromethylphenylboronicacid, pinacol ester
Synonyms : 3-AMINO-5-TRIFLUOROMETHYLPHENYLBORONICACID |
3-Amino-5-trifluoromethylphenylboronicacid pinacol ester
CAS No : 510771-54-7
Purity : 95%
MolecularFormula : C13H17BF3NO2
Molecular Weight: 287.1
Appearance: Liquid
Advanced Synthetic ApplicationsThis boronic acid pinacol ester serves as an essential intermediate in complex organic synthesis, notably in Suzuki-Miyaura cross-coupling reactions. Its molecular structure allows for versatile chemical modifications, making it ideal for developing pharmaceutical and agrochemical compounds. Researchers benefit from its ease of incorporation into multi-step synthetic routes.
Safe Handling and StorageTo preserve its stability, 3-amino-5-trifluoromethylphenylboronic acid, pinacol ester should be kept dry and protected from air. Employing gloves, eye protection, and a working fume hood are recommended precautions. The product is packaged in sealed containers and available in various quantities, ensuring convenient, safe usage for laboratory and industrial requirements.
FAQs of 3-Amino-5-trifluoromethylphenylboronic acid, pinacol ester:
Q: How should 3-amino-5-trifluoromethylphenylboronic acid, pinacol ester be stored for maximum stability?
A: It is best stored in a cool, dry place under an inert atmosphere, away from moisture and air. Sealed containers help maintain stability, and adherence to these conditions ensures a shelf life of up to 24 months.
Q: What are the primary applications of this compound in research and industry?
A: This compound is widely employed as a building block in the synthesis of pharmaceuticals, novel organic molecules, and agrochemicals, with particular value in cross-coupling reactions such as Suzuki-Miyaura.
Q: When is it necessary to use personal protective equipment while handling this product?
A: Personal protective equipment such as gloves and eye protection should always be worn when handling this substance. Use under a fume hood is recommended due to its sensitivity to air and moisture.
Q: Where is this compound typically used within laboratory processes?
A: It is commonly found in organic synthesis laboratories, especially where the construction of complex molecular frameworks is required, including drug and agrochemical development.
Q: What are the key benefits of using the pinacol ester form of 3-amino-5-trifluoromethylphenylboronic acid?
A: The pinacol ester offers improved handling and solubility in organic solvents, enhancing its utility in various chemical processes. Its stability under recommended conditions also contributes to a longer shelf life and reliable performance in synthesis.
Q: Is there any hazard classification for this compound according to current safety regulations?
A: According to the Globally Harmonized System (GHS), this product is not classified as hazardous. Nonetheless, standard safety procedures should always be observed.